Blood Clots Associated with Oral Contraceptives Yaz and Yasmin

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Bayer Healthcare, the maker of the Yaz and Yasmin branded birth control pills, is facing a lawsuit based on allegations that the products can cause potentially fatal blood clots. The lawsuit alleges that Yaz caused the plaintiff, a woman of childbearing age, to have a pulmonary embolism.

At the heart of the issue is the new combination of hormones used in Yaz/Yasmin, namely drospirenone and ethinylestradiol, which appear to be associated with a risk for blood clots, in addition to a lengthy list of side effects and contraindications. Key adverse effects include heart attack, stroke, kidney disease, deep vein thrombosis and gallbladder disease, in addition to pulmonary embolism.

The lawsuit recently filed in the US states "In April 2002, the British Medical Journal reported that the Dutch College of General Practitioners recommended that the older second generation birth control pills be prescribed in lieu of Yasmin, as a result of 40 cases of venous thrombosis among women taking Yasmin."

The complaint also states "In February 2003, a paper entitled Thromboembolism Associated with the New Contraceptive Yasmin was published in the British Medical Journal detailing a Netherlands Pharmacovigilance Center report of five additional reports of thromboembolism where Yasmin was suspected as the cause, including two deaths."

Since its approval by the FDA in 2006 for both birth control and treatment of PMDD (Premenstrual Dysphoric Disorder), Yaz has become widely prescribed. The allegations of increased risk for blood clots and life-threatening adverse events are cause for concern, and similar to those made against two other popular birth control devices, namely Nuvaring by Schering-Plough and the Ortho Evra patch, by Johnson and Johnson.

JUN-23-09: Bayer Sued Over Yaz Death, Blood Clots [BNET: BAYER SUED OVER YAZ DEATH, BLOOD CLOTS]

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