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Patent Profile: Immunomedics Announces Patent for Dock-and-Lock Antibody Assemblies

By Donald Zuhn, Kevin Noonan, Chris Singer, Sherri Oslick, and Jason Derry

By Mark Chael -- On May 5th, Immunomedics, Inc. announced that its majority-owned subsidiary, IBC Pharmaceuticals, Inc., was granted U.S. Patent No. 7,527,787, entitled "Multivalent Immunoglobulin-based Bioreactive Assemblies." Claim 1 from the patent reads: 1. A hexameric stably tethered structure comprising an IgG antibody attached to two AD2 moieties of SEQ ID NO: 4 and four antigen-binding antibody fragments of the same or different IgG with each fragment attached to a DDD2 moiety of SEQ ID NO: 2; the AD2 moieties bound to the DDD2 moieties. The four antigen-binding antibody fragments can be Fab fragments. In particular, these Fab fragments...

Full post as published by Patent Docs on May 13, 2009 (boomark / email).