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: A Georgia Lawyer

Necrosis Caused by Intra-arterial Injection of Promethazine: Case Report

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I found this report after hearing more about the recent black box warning issued by the FDA regarding Promethazine:

"The first reported cases of intra-arterial promethazine (Phenergan) injection causing complications were in the late 1960s." There have been literature reports of adverse outcomes after accidental intra-arterial injections of drugs since the 1940s.

The study presented two cases of intra-arterial promethazine injection that led to digital necrosis. Both cases eventually led to amputations.


The study may be found here.

Full post as published by A Georgia Lawyer on September 21, 2009 (boomark / email).

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