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RNAi Patent Revoked by EPO

By Donald Zuhn, Kevin Noonan, Chris Singer, Sherri Oslick, and Jason Derry

By Kevin E. Noonan -- Last Friday, the European Patent Office revoked (in its entirety) European Patent No. EP 1 230 375, owned by Cancer Research Therapeutics Ltd. of Cambridge, UK and exclusively licensed to Alnylam Pharmaceuticals, Inc. The patent was opposed by several companies involved in commercializing RNA interference (RNAi), including Sanofi-Aventis Deutschland GmbH, Sirna Therapeutics, Nucleonics, Inc., Quark Biotech, and Silence Therapeutics AG. The patent, commonly referred to as the "Glover patent" based on the name of the first inventor, contained broad claims but were also limited by disclosure of (relatively) long double-stranded RNA species, which have been...

Full post as published by Patent Docs on July 15, 2008 (boomark / email).