Personal Injury Law

Mesothelioma risk among those exposed to chrysotile asbestos only and mixtures that include amphibole: a case?control study in the USA, 1975?1980

Posted on November 04, 2020
Objectives Occupational asbestos exposure is causally linked to mesothelioma. However, whether exposure to only chrysotile asbestos is associated with mesothelioma risk, and the heterogeneity in risk by different fibre types/lengths remains unclear. We investigated whether mesothelioma risk differs among workers exposed to only chrysotile asbestos compared with chrysotile and amphibole (ie, amosite, tremolite, anthophyllite and […] The post Mesothelioma risk among those exposed to chrysotile asbestos only and mixtures that include amphibole: a case?control study in the USA, 1975?1980 appeared first on Law Offices of Thomas J...

Biomarker candidates could aid in earlier diagnosis of mesothelioma

Posted on October 21, 2020
Mesothelioma is a deadly cancer mainly caused by exposure to asbestos fibers. Unfortunately, mesothelioma is generally diagnosed at an already advanced stage and none of the therapeutic strategies tried so far is able to eradicate the disease. So new biomarkers that could help to identify the disease at an earlier stage are urgently needed...

A multicentre randomised phase III trial comparing pembrolizumab vs single-agent chemotherapy for advanced pre-treated malignant pleural mesothelioma: the European Thoracic Oncology Platform (ETOP 9-15) PROMISE-meso trial

Posted on October 15, 2020
Background:  Malignant pleural mesothelioma (MPM) is an aggressive malignancy characterized by limited treatment options and a poor prognosis. At relapse after platinum-based chemotherapy, single-agent chemotherapy is commonly used and single-arm trials of immune-checkpoint inhibitors have demonstrated encouraging activity...

FDA Approves Drug Combination for Treating Mesothelioma

Posted on October 08, 2020
[On October 02, 2020], the U.S. Food and Drug Administration approved Opdivo (nivolumab) in combination with Yervoy (ipilimumab) [– nivolumab plus ipilimumab –] for the first-line treatment of adults with malignant pleural mesothelioma that cannot be removed by surgery...

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Durvalumab with first-line chemotherapy in previously untreated malignant pleural mesothelioma (DREAM): a multicentre, single-arm, phase 2 trial with a safety run-in

Posted on September 23, 2020
Background:  There is a strong unmet need to improve systemic therapy in mesothelioma. Chemotherapy with cisplatin and pemetrexed improves survival in malignant pleural mesothelioma, and immune checkpoint inhibitors are an emerging treatment in this disease...

FDA clears IND application for CAR T-cell therapy for advanced mesothelioma

Posted on September 17, 2020
The FDA cleared an investigational new drug application for ATA2271, a chimeric antigen receptor T-cell therapy [ or CAR T-cell therapy ] for the treatment of advanced mesothelioma, according to the agent?s manufacturer. ATA2271 (Atara Biotherapeutics) is an autologous CAR T-cell therapy that targets the mesothelin antigen expressed on the surface of certain solid tumors...

Phase I Study of Novel Drug Shows Preliminary Activity in Mesothelin-Expressing Tumors

Posted on September 09, 2020
Data from a Phase I study published last week in the Journal of Clinical Oncology showed that Bayer’s investigational compound anetumab ravtansine (BAY 94-9343), an antibody-drug conjugate comprising an anti-mesothelin antibody linked to maytansinoid DM4, was well tolerated in patients with advanced, metastatic, or recurrent solid tumors that expressed the tumor-differentiation antigen mesothelin...

Telomerase reverse transcriptase promoter mutations identify a genomically defined and highly aggressive human pleural mesothelioma subgroup

Posted on August 31, 2020
Purpose: Human malignant pleural mesothelioma (MPM) is characterized by dismal prognosis. Consequently, dissection of molecular mechanisms driving malignancy is of key importance. Here we investigate, whether activating mutations in the telomerase reverse transcriptase (TERT) gene promoter are present in MPM and associated with disease progression, cell immortalization, and genomic alteration patterns...

Chemical Firm BASF and Its Law Firm to Pay $72.5M to Close Talcum-Asbestos Claims

Posted on August 20, 2020
BASF SE, the world?s biggest chemical maker, and a law firm agreed to pay a combined $72.5 million to resolve claims they hid evidence that certain talc products contained asbestos in an effort to scuttle thousands of lawsuits. Executives of BASF, along with lawyers from the New York-based Cahill, Gordon & Reindel LLP, agreed to […] The post Chemical Firm BASF and Its Law Firm to Pay $72...

Clinical Practice Guidelines for the Management of Malignant Pleural Mesothelioma

Posted on August 13, 2020
Clinical practice guidelines for the management of malignant pleural mesothelioma were released in May 2020 by the European Respiratory Society, European Society of Thoracic Surgeons, European Association for Cardio-Thoracic Surgery, and European Society for Radiotherapy and Oncology...

Nivolumab/Ipilimumab Demonstrates Durable OS Benefit in Malignant Pleural Mesothelioma

Posted on August 10, 2020
[ A nivolumab plus ipilimumab combination ] significantly improved overall survival (OS) versus chemotherapy in the first-line treatment of patients with unresectable malignant pleural mesothelioma, according to findings from a prespecified analysis of the phase 3 CheckMate-743 trial (NCT02899299) that were presented during the 2020 International Association for the Study of Lung Cancer?s World Conference […] The post Nivolumab/Ipilimumab Demonstrates Durable OS Benefit in Malignant Pleural Mesothelioma appeared first on Law Offices of Thomas J...

Private Settlement Reached in Mesothelioma Case

Posted on July 29, 2020
A private settlement was reached in a mass litigation asbestos case [on July 28, 2020] in Ohio County [(West Virginia)] Circuit Court, meaning a trial set to take place at The Highlands Event Center next week won?t be necessary. Both Ohio County Clerk of Courts Brenda Miller and court employees for Judge Ronald Wilson said […] The post Private Settlement Reached in Mesothelioma Case appeared first on Law Offices of Thomas J...

Questioning the prognostic role of BAP-1 immunohistochemistry in malignant pleural mesothelioma: A single center experience with systematic review and meta-analysis

Posted on July 16, 2020
Introduction:  The prognostic role of BRCA1 associated protein-1 (BAP1) expression in malignant pleural mesothelioma (MPM) is a matter of debate. We aimed to clarify whether MPM patients with loss of BAP1 expression have better overall survival (OS) compared to BAP1 positive patients...

Study finds drug beneficial for shrinking mesothelioma tumors

Posted on July 08, 2020
A drug that is designed to boost the immune system against mesothelioma, when combined with immunotherapy, was found to be beneficial in a small study involving ten patients. The results, which appeared July 1, 2020, in Science Translational Medicine, suggest that the drug LMB-100 could prolong the life of some patients with advanced disease...

Pfizer, Quigley Seek Court Approval of Asbestos Settlement ? Bloomberg

Posted on March 23, 2011
Quoted from http://www.bloomberg.com/news/2011-03-22/pfizer-reaches-asbestos-settlement-that-may-end-quigley-unit-s-bankruptcy.html Pfizer, Quigley Seek Court Approval of Asbestos Settlement By Tiffany Kary – Mar 22, 2011 4:24 PM ET Pfizer Inc. (PFE), the world’s largest drugmaker, reached a settlement with asbestos claimants that may bring an end to its Quigley unit’s seven-year-old bankruptcy case...

Newport News jury hands down $25 million verdict against Exxon in asbestos case

Posted on March 18, 2011
Quoted from http://www.baltimoresun.com/dp-nws-asbestos-verdict-20110317,0,4639148.story Newport News jury hands down $25 million verdict against Exxon in asbestos case The jury verdict will be reduced to $17.5 million, and Exxon is expected to appeal By Peter Dujardin, pdujardin@dailypress...

Owens-Illinois denies asbestos conspiracy claim

Posted on March 15, 2011
Quoted from http://www.businessweek.com/ap/financialnews/D9LV9URO1.htm Owens-Illinois denies asbestos conspiracy claim   PERRYSBURG, Ohio Major glass manufacturer Owens-Illinois Inc. said Monday it is disappointed by a jury verdict assessing more than $40 million in damages against it in a case of alleged injuries from asbestos...

A LICHFIELD widow whose husband died from an asbestos-related cancer is suing for damages of up to £350,000.

Posted on February 24, 2011
Quoted from http://www.thisislichfield.co.uk/news/Widow-sues-husband-s-death-asbestos-cancer/article-3260847-detail/article.html Widow sues over husband’s death from asbestos cancer   A LICHFIELD widow whose husband died from an asbestos-related cancer is suing for damages of up to £350,000...

Product labels are not hearsay, cancer victim?s family tells Calif. appeals court

Posted on January 25, 2011
Quoted from http://westlawnews.thomson.com/California_Litigation/News/2011/01_-_January/Product_labels_are_not_hearsay,_cancer_victim_s_family_tells_Calif__appeals_court/ Product labels are not hearsay, cancer victim’s family tells Calif. appeals court 1/24/2011 A trial judge?s ruling that offering a product label as evidence the package contained the product noted on the label was inadmissible hearsay is an extreme, unsupportable reading of the law, plaintiffs in a California friction-products suit say...

Exposure to asbestos blamed for cancer

Posted on January 21, 2011
Quoted from http://www.burtonmail.co.uk/News/Exposure-to-asbestos-blamed-for-cancer.htm Make Us Your Homepage Published: 21/01/2011 08:00 Exposure to asbestos blamed for cancer by CHRISTINA MASSEY A 79-YEAR-OLD man died of a disease that lay dormant in his system for [...

Back off on asbestos: poll

Posted on January 17, 2011
Quoted from http://www.montrealgazette.com/business/Back+asbestos+poll/4112687/story.html Back off on asbestos: poll By MICHELLE LALONDE, The Gazette January 15, 2011 More than three-quarters of Quebecers oppose the idea of the Quebec government financing a project to expand the Jeffrey asbestos mine, according to a survey commissioned by the Canadian Association of Physicians for the [...

Agonising death of Oxford cancer victim

Posted on January 14, 2011
Quoted from http://www.oxfordtimes.co.uk/news/8790507.Agonising_death_of_Oxford_cancer_victim/ Agonising death of Oxford cancer victim 9:30am Friday 14th January 2011 A HOSPITAL last night pledged to make changes to drug trials after an Oxford cancer sufferer endured an “unimaginable nightmare” and died while testing a new treatment...

Asbestosis was cause of deaths ? inquest

Posted on January 07, 2011
Quoted from http://www.scarborougheveningnews.co.uk/news/local/asbestosis_was_cause_of_deaths_inquest_1_2908188 Asbestosis was cause of deaths ? inquest Published on Fri Jan 07 09:51:39 GMT 2011   AN INQUEST heard how a 67-year-old former scaffolder contracted a fatal disease after being exposed to asbestos in the workplace...

Malignant Mesothelioma ? Many Hidden Cases

Posted on January 07, 2011
Quoted from http://www.medscape.com/viewarticle/735359 Malignant Mesothelioma — Many Hidden Cases Zosia Chustecka January 6, 2011 ? Cases of malignant mesothelioma, caused almost exclusively by exposure to asbestos, are significantly underreported worldwide, concludes a new study published online January 6 in Environmental Health Perspectives...

The deadly legacy of the asbestos factory to one family

Posted on December 21, 2010
Quoted from http://www.hebdenbridgetimes.co.uk/news/local/the_deadly_legacy_of_the_asbestos_factory_to_one_family_1_2863621 The deadly legacy of the asbestos factory to one family Published on Mon Dec 20 16:35:02 GMT 2010 A WOMAN whose parents worked at the Cape Asbestos factory, Old Town, died of mesothelioma ? the cancer caused by the deadly mineral...

Travelers Ordered to Pay $500 Million to Johns Manville Asbestos Victims

Posted on December 17, 2010
Quoted from http://www.bloomberg.com/news/2010-12-16/travelers-must-pay-for-johns-manville-s-asbestos-settlements-judge-rules.html Travelers Ordered to Pay $500 Million to Johns Manville Asbestos Victims By Tiffany Kary - Dec 16, 2010 1:11 PM ET Travelers Cos...

Asbestos claims continue to rise

Posted on December 10, 2010
Quoted from http://www.abc.net.au/news/stories/2010/12/10/3089792.htm Asbestos claims continue to rise Posted Fri Dec 10, 2010 8:44am AEDT The latest figures from the New South Wales Dust Diseases Board reveals that payouts for the asbestos caused disease mesothelioma are continuing to increase...

Lancet, Asian delegation urge Canada to ban asbestos exports

Posted on December 09, 2010
Quoted from http://www.theglobeandmail.com/news/national/lancet-asian-delegation-urge-canada-to-ban-asbestos-exports/article1830597/ Lancet, Asian delegation urge Canada to ban asbestos exports RHÉAL SÉGUIN AND AND CARLY WEEKS QUEBEC AND TORONTO? From Thursday’s Globe and Mail Published Wednesday, Dec...

Federal loan to give certainty to asbestos victims

Posted on December 07, 2010
Quoted from http://www.abc.net.au/news/stories/2010/12/07/3086671.htm Federal loan to give certainty to asbestos victims Updated December 7, 2010 11:45:00 The Federal Government has announced it will lend up to $160 million to the New South Wales Government to help compensate James Hardie asbestos victims...

The ethics of selling asbestos

Posted on December 07, 2010
Quoted from http://www.digitaljournal.com/article/301128 The ethics of selling asbestos By KJ Mullins. December 6, 2010 In Canada asbestos has been banned for use but that doesn’t stop the mining and exportation of the leading cause of a rare cancer known as mesothelioma from the remaining two mines located in Quebec...

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