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Gene Therapy Experiencing a Revival

By Donald Zuhn, Kevin Noonan, Chris Singer, Sherri Oslick, and Jason Derry

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By James DeGiulio -- After over a decade of suspicion following the death of an 18-year-old patient, gene therapy is experiencing a revival among scientists and drugmakers, according to a recent Bloomberg report ("'Dead as Doornail' Gene Therapy Revival Spurs Genzyme"). Since the patient's death in 1999, scientists have linked many of the safety problems with gene therapy to the modified adenovirus vectors used to deliver the gene. Current trials utilize a new generation of gene delivery vectors, such as adeno-associated virus (AAV), which trigger a milder immune response than the adenovirus used in previous studies and are consequently much...

Full post as published by Patent Docs on May 04, 2010 (boomark / email).

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